Description
Coartem (artemether/lumefantrine) is an antimalarial medication used to treat non-severe malaria. Coartem does not prevent malaria.
What Are Side Effects of Coartem?
Common side effects of Coartem include:
- headache,
- dizziness,
- loss of appetite,
- weakness,
- fever,
- chills,
- tiredness,
- muscle or joint pain,
- nausea,
- vomiting,
- abdominal pain,
- cough, and
- trouble sleeping (insomnia).
Seek immediate medical attention if you have rare but very serious side effects of Coartem including:
- chest pain,
- severe dizziness,
- fainting, or
- fast/irregular/pounding heartbeat.
Coartem may cause serious side effects including:
- worsening malaria symptoms,
- severe vomiting,
- loss of appetite,
- unable to eat,
- fast or pounding heartbeats,
- lightheadedness, and
- skin rash, no matter how mild
Get medical help right away, if you have any of the symptoms listed above.
Seek medical care or call 911 at once if you have the following serious side effects:
- Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
- Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheartedness, or passing out;
- Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.
This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.
Dosage for Coartem?
A 3-day treatment schedule of Coartem with a total of 6 doses is recommended for adult patients with a bodyweight of 35 kg and above: Four tablets as a single initial dose, 4 tablets again after 8 hours and then 4 tablets twice daily (morning and evening) for the following two days (total course of 24 tablets). Pediatric dose is determined by the child’s weight.
What Drugs, Substances, or Supplements Interact with Coartem?
Coartem may interact with ketoconazole, cold or allergy medicines, antibiotics, antidepressants, heart rhythm medication, HIV or AIDS medicine, medicine to prevent or treat nausea and vomiting, medicines to treat psychiatric disorders, migraine headache medicines, or narcotics. Tell your doctor all medications you use.
Coartem During Pregnancy and Breastfeeding
During pregnancy, Coartem should be used only when prescribed. It is unknown if this medication passes into breast milk and the effect on a nursing infant is unknown. Consult your doctor before breastfeeding.
Additional Information
Our Coartem (artemether/lumefantrine) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.





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