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Amatem softgel 20\120 x 24tabs

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Amatem softgel 20\120 x18

2,150.00

Artemether and Lumefantrine Capsule should be taken with high fat food or drinks such as milk.
Note that patients with acute malaria are frequently averse to food. Patients should be encouraged
to resume normal eating as soon as food can be tolerated since this improves absorption of
artemether and lumefantrine. In the event of vomiting within 1 hour of administration a repeat dose
should be taken.
For adults and children weighing 35 kg and above a standard three days treatment schedule with a
total of 8 doses is recommended as follows: four capsules as a single dose at the time of initial
diagnosis, again four capsules after eight hours and then four capsules twice daily (morning and
evening) on each of the following two days.
For Adults and children weighing 25 to less than 35 kg, a six-dose regimen is recommended with
three capsules as a single dose at the time of initial diagnosis, again three capsules after eight hours
and then three capsules twice daily (morning and evening) on each of the following two days.
For Adults and children weighing 15 to less than 25 kg, a four-dose regimen is recommended with
two capsules as a single dose at the time of initial diagnosis, again two capsules after eight hours
and then two capsules twice daily (morning and evening) on each of the following two days.
Dosage in elderly patients
Although no studies have been carried out in the elderly, no special precautions or dosage
adjustments are considered necessary in such patients.

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Description

Artemether and Lumefantrine tablets are indicated for the treatment of P. falciparum malaria cases resistant to both Chloroquine and Sulphadoxine-Pyrimethamine combination.
The combination is recommended for first line treatment of malaria.

Artemether and Lumefantrine combination is a fixed dose Artemisinin-based Combination Therapy (ACT) combining Artemether, an artemisinin derivative, and Lumefantrine, a synthetic antimalarial drug. Artemether is a sesquiterpene lactone derived from artemisinin. Artemisinin is a compound derived from the sweet wormwood plant and has been used for centuries in traditional Chinese medicine to treat fever. Lumefantrine is a synthetic aryl-amino alcohol antimalarial (Quinine, Mefloquine and Halofantrine are members of the same group).

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