Chloroquine phosphate BP Injection for I.M & IV Per Vial

Description

Indications

Chloroquine phosphate is indicated for:

• Treatment of malaria: Effective against Plasmodium vivax, P. malariae, P. ovale, and susceptible strains of P. falciparum
• Treatment of extraintestinal amebiasis: A liver infection caused by protozoa

Dosage

The dosage of chloroquine phosphate varies based on the condition being treated:

• Malaria Treatment: Initial dose of 1 g (600 mg base), followed by 500 mg (300 mg base) after 6-8 hours, then 500 mg (300 mg base) at 24 and 48 hours after the initial dose.
• Amebiasis treatment: 1 g (600 mg base) daily for 2 days, followed by 500 mg (300 mg base) daily for 14-21 days.

Side Effects

Common side effects include:

• Nausea, vomiting, diarrhea, stomach cramps
• Headache
• Changes in mood or behavior
• Hair loss or changes in hair/skin color.

Serious side effects may include:

• Seizures
• Severe muscle weakness
• Vision changes (e.g., blurred vision, trouble focusing)
• Heart problems (e.g fast or pounding heartbeats, dizziness)

Precautions

• Heart Conditions: Chloroquine can cause serious heart problems, especially if used with other medications that affect heart rhythm. It’s crucial to inform your doctor if you have any heart issues.
• Liver Disease: Use with caution in patients with liver disease or alcoholism, as chloroquine can affect liver function.
• Eye Health: Long-term use may cause irreversible damage to the retina of the eye. Regular eye exams are recommended if you are on prolonged treatment.
• Pregnancy and Breastfeeding: Consult a healthcare provider before use, as chloroquine can cross the placenta and is excreted in breast milk.
• Blood Disorders: Inform your doctor if you have any blood disorders, as chloroquine can affect blood cell counts.
• Neurological Conditions: Use with caution if you have a history of seizures or other neurological conditions.
• Allergic Reactions: Be aware of any allergic reactions to chloroquine or similar medications. Seek immediate medical attention if you experience symptoms like rash, itching, or swelling.